6MKQ
Carbapenemase VCC-1 bound to avibactam
Summary for 6MKQ
| Entry DOI | 10.2210/pdb6mkq/pdb |
| Descriptor | Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide (3 entities in total) |
| Functional Keywords | carbapenemase, vcc-1, avibactam, beta-lactamase, vibrio cholerae, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Vibrio cholerae |
| Total number of polymer chains | 1 |
| Total formula weight | 29497.16 |
| Authors | Mark, B.L.,Vadlamani, G. (deposition date: 2018-09-26, release date: 2019-01-30, Last modification date: 2023-10-11) |
| Primary citation | Mangat, C.S.,Vadlamani, G.,Holicek, V.,Chu, M.,Larmour, V.L.C.,Vocadlo, D.J.,Mulvey, M.R.,Mark, B.L. Molecular Basis for the Potent Inhibition of the Emerging Carbapenemase VCC-1 by Avibactam. Antimicrob. Agents Chemother., 63:-, 2019 Cited by PubMed: 30782990DOI: 10.1128/AAC.02112-18 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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