6MKI

Crystal structure of penicillin-binding protein 4 (PBP4) from Enterococcus faecalis in the ceftaroline-bound form

Summary for 6MKI

Entry DOI	10.2210/pdb6mki/pdb
Descriptor	penicillin-binding protein 4 (PBP4), Ceftaroline, bound form, PHOSPHATE ION, ... (5 entities in total)
Functional Keywords	pbp, antibiotic, penicillin-binding protein, protein binding-antibiotic complex, protein binding/antibiotic
Biological source	Enterococcus faecalis
Total number of polymer chains	1
Total formula weight	71598.87
Authors	D'Andrea, E.D.,Moon, T.M.,Peti, W.,Page, R. (deposition date: 2018-09-25, release date: 2018-10-31, Last modification date: 2024-04-03)
Primary citation	Moon, T.M.,D'Andrea, E.D.,Lee, C.W.,Soares, A.,Jakoncic, J.,Desbonnet, C.,Garcia-Solache, M.,Rice, L.B.,Page, R.,Peti, W. The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance. J. Biol. Chem., 293:18574-18584, 2018 Cited by PubMed: 30355734 DOI: 10.1074/jbc.RA118.006052 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.984 Å)

Structure validation