6MKI

Crystal structure of penicillin-binding protein 4 (PBP4) from Enterococcus faecalis in the ceftaroline-bound form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008658	molecular_function	penicillin binding
A	0046677	biological_process	response to antibiotic
A	0071555	biological_process	cell wall organization
A	0071972	molecular_function	peptidoglycan L,D-transpeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue AI8 A 701

Chain	Residue
A	SER424
A	THR622
A	ALA623
A	GLU624
A	PO4702
A	VAL467
A	SER482
A	ASN484
A	GLY541
A	GLN542
A	TYR605
A	THR620
A	GLY621

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site_id	AC2
Number of Residues	4
Details	binding site for residue PO4 A 702

Chain	Residue
A	THR622
A	SER637
A	SER663
A	AI8701

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site_id	AC3
Number of Residues	5
Details	binding site for residue PO4 A 703

Chain	Residue
A	PHE559
A	ASN562
A	ASN589
A	ARG644
A	ASN647

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site_id	AC4
Number of Residues	3
Details	binding site for residue GOL A 704

Chain	Residue
A	GLY183
A	GLY185
A	ILE188

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