6MKI
Crystal structure of penicillin-binding protein 4 (PBP4) from Enterococcus faecalis in the ceftaroline-bound form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008658 | molecular_function | penicillin binding |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0071555 | biological_process | cell wall organization |
| A | 0071972 | molecular_function | peptidoglycan L,D-transpeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue AI8 A 701 |
| Chain | Residue |
| A | SER424 |
| A | THR622 |
| A | ALA623 |
| A | GLU624 |
| A | PO4702 |
| A | VAL467 |
| A | SER482 |
| A | ASN484 |
| A | GLY541 |
| A | GLN542 |
| A | TYR605 |
| A | THR620 |
| A | GLY621 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 702 |
| Chain | Residue |
| A | THR622 |
| A | SER637 |
| A | SER663 |
| A | AI8701 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 703 |
| Chain | Residue |
| A | PHE559 |
| A | ASN562 |
| A | ASN589 |
| A | ARG644 |
| A | ASN647 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 704 |
| Chain | Residue |
| A | GLY183 |
| A | GLY185 |
| A | ILE188 |
