6MK5
Solution NMR structure of spider toxin analogue [F5A,M6F,T26L,K28R]GpTx-1
Summary for 6MK5
Entry DOI | 10.2210/pdb6mk5/pdb |
NMR Information | BMRB: 30522 |
Descriptor | Toxin GTx1-15 (1 entity in total) |
Functional Keywords | gptx-1 analogue, spider toxin, peptide-membrane interactions, voltage-sensitive sodium channels, toxin |
Biological source | Grammostola porteri (Tarantula spider) |
Total number of polymer chains | 1 |
Total formula weight | 4068.86 |
Authors | Schroeder, C.I. (deposition date: 2018-09-25, release date: 2018-12-19, Last modification date: 2023-06-14) |
Primary citation | Lawrence, N.,Wu, B.,Ligutti, J.,Cheneval, O.,Agwa, A.J.,Benfield, A.H.,Biswas, K.,Craik, D.J.,Miranda, L.P.,Henriques, S.T.,Schroeder, C.I. Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1. ACS Chem. Biol., 14:118-130, 2019 Cited by PubMed: 30507158DOI: 10.1021/acschembio.8b00989 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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