6MJZ

Cryo-EM structure of Human Parainfluenza Virus Type 3 (hPIV3) in complex with antibody PIA174

6MJZ の概要

• エントリーDOI: 10.2210/pdb6mjz/pdb
• EMDBエントリー: 9135
• 分子名称: Fusion glycoprotein F0, PIA174 Fab Heavy chain, PIA174 Fab Light chain (3 entities in total)
• 機能のキーワード: hpiv3 envelope, asymmetric, complex, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human parainfluenza virus 3; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 211110.57

構造登録者

Acharya, P.,Stewart-Jones, G.,Carragher, B.,Potter, C.S.,Kwong, P.D. (登録日: 2018-09-24, 公開日: 2018-11-14, 最終更新日: 2019-12-18)

• 主引用文献: Stewart-Jones, G.B.E.,Chuang, G.Y.,Xu, K.,Zhou, T.,Acharya, P.,Tsybovsky, Y.,Ou, L.,Zhang, B.,Fernandez-Rodriguez, B.,Gilardi, V.,Silacci-Fregni, C.,Beltramello, M.,Baxa, U.,Druz, A.,Kong, W.P.,Thomas, P.V.,Yang, Y.,Foulds, K.E.,Todd, J.P.,Wei, H.,Salazar, A.M.,Scorpio, D.G.,Carragher, B.,Potter, C.S.,Corti, D.,Mascola, J.R.,Lanzavecchia, A.,Kwong, P.D.; Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4.; Proc. Natl. Acad. Sci. U.S.A., 115:12265-12270, 2018; PubMed: 30420505; DOI: 10.1073/pnas.1811980115

実験手法

ELECTRON MICROSCOPY (4.3 Å)