6MHG
Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts
Summary for 6MHG
Entry DOI | 10.2210/pdb6mhg/pdb |
EMDB information | 9114 |
Descriptor | circumsporozoite protein, Fab311 heavy chain, Fab311 light chain (3 entities in total) |
Functional Keywords | plasmodium falciparum, antibody, csp, rscsp, immune system |
Biological source | Plasmodium falciparum More |
Total number of polymer chains | 23 |
Total formula weight | 548105.13 |
Authors | |
Primary citation | Oyen, D.,Torres, J.L.,Cottrell, C.A.,Richter King, C.,Wilson, I.A.,Ward, A.B. Cryo-EM structure ofP. falciparumcircumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts. Sci Adv, 4:eaau8529-eaau8529, 2018 Cited by PubMed: 30324137DOI: 10.1126/sciadv.aau8529 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.57 Å) |
Structure validation
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