6MGP

Structure of human 4-1BB / 4-1BBL complex

6MGP の概要

• エントリーDOI: 10.2210/pdb6mgp/pdb
• 関連するPDBエントリー: 6mge
• 分子名称: Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: signaling, tnfrsf, tnfsf, 4-1bb, cd137, 4-1bbl, cd137l, immune system, complex
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 115638.86

構造登録者

Kimberlin, C.R.,Chin, S.M.,Roe-Zurz, Z.,Xu, A.,Yang, Y. (登録日: 2018-09-14, 公開日: 2018-11-14, 最終更新日: 2023-10-11)

• 主引用文献: Kimberlin, C.R.,Chin, S.M.,Roe-Zurz, Z.,Zhang, P.,Xu, A.,Liao-Chan, S.,Debasish, S.,Nager, A.R.,Schirle Oakdale, N.,Brown, C.,Wang, F.,Yang, Y.,Lindquist, K.,Yeung, Y.A.,Salek-Ardakani, S.,Chaparro-Riggers, J.; Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab; Nat Commun, 9:4679-4691, 2018

実験手法

X-RAY DIFFRACTION (2.13 Å)