6MFN
Human Argonaute2-miR-27a bound to HSUR1 target RNA
Summary for 6MFN
Entry DOI | 10.2210/pdb6mfn/pdb |
Descriptor | Protein argonaute-2, RNA (5'-R(P*UP*UP*CP*AP*CP*AP*GP*UP*G)-3'), RNA (5'-R(P*UP*CP*UP*GP*UP*GP*AP*UP*AP*A)-3'), ... (5 entities in total) |
Functional Keywords | rna-binding protein, microrna, target directed microrna decay, hydrolase-rna complex, hydrolase/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 111146.50 |
Authors | Sheu-Gruttadauria, J.,MacRae, I.J. (deposition date: 2018-09-11, release date: 2019-08-07, Last modification date: 2023-10-11) |
Primary citation | Sheu-Gruttadauria, J.,Pawlica, P.,Klum, S.M.,Wang, S.,Yario, T.A.,Schirle Oakdale, N.T.,Steitz, J.A.,MacRae, I.J. Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75:1243-, 2019 Cited by PubMed: 31353209DOI: 10.1016/j.molcel.2019.06.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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