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6MCP

L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex with human MOB1A

Summary for 6MCP
Entry DOI10.2210/pdb6mcp/pdb
DescriptorLegK7, MOB kinase activator 1A, TETRAETHYLENE GLYCOL, ... (9 entities in total)
Functional Keywordstranslocated effector, ser/thr protein kinase, allosteric activation, hippo pathway, transferase
Biological sourceLegionella pneumophila subsp. pneumophila
More
Total number of polymer chains4
Total formula weight169021.95
Authors
Beyrakhova, K.A.,Xu, C.,Boniecki, M.T.,Cygler, M. (deposition date: 2018-09-01, release date: 2019-09-04, Last modification date: 2023-10-11)
Primary citationLee, P.C.,Beyrakhova, K.,Xu, C.,Boniecki, M.T.,Lee, M.H.,Onu, C.J.,Grishin, A.M.,Machner, M.P.,Cygler, M.
TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Proc.Natl.Acad.Sci.USA, 117:14433-14443, 2020
Cited by
PubMed: 32513747
DOI: 10.1073/pnas.2000497117
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

數據於2024-03-27公開中

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