6MBK
SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, First P212121 Crystal Form
Summary for 6MBK
Entry DOI | 10.2210/pdb6mbk/pdb |
Descriptor | Actin peptide, Histone-lysine N-methyltransferase setd3, S-ADENOSYL-L-HOMOCYSTEINE, ... (7 entities in total) |
Functional Keywords | transferase, transferase-structural protein complex, transferase/structural protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 141473.43 |
Authors | Horton, J.R.,Dai, S.,Cheng, X. (deposition date: 2018-08-30, release date: 2018-12-19, Last modification date: 2023-10-11) |
Primary citation | Wilkinson, A.W.,Diep, J.,Dai, S.,Liu, S.,Ooi, Y.S.,Song, D.,Li, T.M.,Horton, J.R.,Zhang, X.,Liu, C.,Trivedi, D.V.,Ruppel, K.M.,Vilches-Moure, J.G.,Casey, K.M.,Mak, J.,Cowan, T.,Elias, J.E.,Nagamine, C.M.,Spudich, J.A.,Cheng, X.,Carette, J.E.,Gozani, O. SETD3 is an actin histidine methyltransferase that prevents primary dystocia. Nature, 565:372-376, 2019 Cited by PubMed: 30626964DOI: 10.1038/s41586-018-0821-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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