6MB9

Ternary (neomycin/CoA) structure of AAC-IIIb

Summary for 6MB9

• Entry DOI: 10.2210/pdb6mb9/pdb
• Descriptor: Aac(3)-IIIb protein, COENZYME A, NONAETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: acetyltransferase, promiscuity, gnat, antibiotic resistance, antibiotic, transferase-antibiotic complex, transferase/antibiotic
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 4
• Total formula weight: 122018.40

Authors

Cuneo, M.J.,Kumar, P. (deposition date: 2018-08-29, release date: 2018-11-07, Last modification date: 2023-10-11)

• Primary citation: Kumar, P.,Selvaraj, B.,Serpersu, E.H.,Cuneo, M.J.; Encoding of Promiscuity in an Aminoglycoside Acetyltransferase.; J. Med. Chem., 61:10218-10227, 2018; PubMed: 30347146; DOI: 10.1021/acs.jmedchem.8b01393

Experimental method

X-RAY DIFFRACTION (2.5 Å)