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6M9T

Crystal structure of EP3 receptor bound to misoprostol-FA

Summary for 6M9T
Entry DOI10.2210/pdb6m9t/pdb
DescriptorProstaglandin E2 receptor EP3 subtype, Endolysin chimera, (11alpha,12alpha,13E,16S)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid, SULFATE ION, ... (6 entities in total)
Functional Keywordsgpcr, prostaglandin e2 receptor 3 (ep3), prostaglandin analogue, membrane protein, misoprostol-fa (biologically active free acid), xfel, lcp, t4l
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains1
Total formula weight62262.59
Authors
Primary citationAudet, M.,White, K.L.,Breton, B.,Zarzycka, B.,Han, G.W.,Lu, Y.,Gati, C.,Batyuk, A.,Popov, P.,Velasquez, J.,Manahan, D.,Hu, H.,Weierstall, U.,Liu, W.,Shui, W.,Katritch, V.,Cherezov, V.,Hanson, M.A.,Stevens, R.C.
Crystal structure of misoprostol bound to the labor inducer prostaglandin E2receptor.
Nat. Chem. Biol., 15:11-17, 2019
Cited by
PubMed: 30510194
DOI: 10.1038/s41589-018-0160-y
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

数据于2024-03-27公开中

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