6M8H
Crystal Structure of the R208Q mutant of G(i) subunit alpha-1
Summary for 6M8H
Entry DOI | 10.2210/pdb6m8h/pdb |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | g protein, switch ii region, oncogenic mutation, signaling protein |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 1 |
Total formula weight | 40933.52 |
Authors | Mascarenhas, R.,Goossens, J.,Leverson, B.,Kothawala, S.,Ballicora, M.,Olsen, K.,de freitas, D.,Liu, D. (deposition date: 2018-08-21, release date: 2019-08-21, Last modification date: 2024-03-13) |
Primary citation | Goossens, J.L.,Leverson, B.D.,Kothawala, S.,Mascarenhas, R.,Liu, D.,Ballicora, M.,Olsen, K.W.,de Freitas, D.M. FUNCTIONAL CONSEQUENCES OF ONCOGENIC MUTATIONS IN THE SWITCH II REGION OF Galphai1 and Galphas PROTEINS To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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