6M4V
Crystal structure of MBP fused split FKBP in complex with rapamycin
Summary for 6M4V
| Entry DOI | 10.2210/pdb6m4v/pdb |
| Descriptor | chimera of Maltose/maltodextrin-binding periplasmic protein and Peptidyl-prolyl cis-trans isomerase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, ... (5 entities in total) |
| Functional Keywords | rapamycin, complex, kinase, isomerase |
| Biological source | Escherichia coli K-12 More |
| Total number of polymer chains | 4 |
| Total formula weight | 107043.63 |
| Authors | Kikuchi, M.,Wu, D.,Inoue, T.,Umehara, T. (deposition date: 2020-03-09, release date: 2020-08-26, Last modification date: 2023-11-29) |
| Primary citation | Wu, H.D.,Kikuchi, M.,Dagliyan, O.,Aragaki, A.K.,Nakamura, H.,Dokholyan, N.V.,Umehara, T.,Inoue, T. Rational design and implementation of a chemically inducible heterotrimerization system. Nat.Methods, 17:928-936, 2020 Cited by PubMed: 32747768DOI: 10.1038/s41592-020-0913-x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.92 Å) |
Structure validation
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