6M4V

Crystal structure of MBP fused split FKBP in complex with rapamycin

6M4V の概要

• エントリーDOI: 10.2210/pdb6m4v/pdb
• 分子名称: chimera of Maltose/maltodextrin-binding periplasmic protein and Peptidyl-prolyl cis-trans isomerase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, ... (5 entities in total)
• 機能のキーワード: rapamycin, complex, kinase, isomerase
• 由来する生物種: Escherichia coli K-12; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 107043.63

構造登録者

Kikuchi, M.,Wu, D.,Inoue, T.,Umehara, T. (登録日: 2020-03-09, 公開日: 2020-08-26, 最終更新日: 2023-11-29)

• 主引用文献: Wu, H.D.,Kikuchi, M.,Dagliyan, O.,Aragaki, A.K.,Nakamura, H.,Dokholyan, N.V.,Umehara, T.,Inoue, T.; Rational design and implementation of a chemically inducible heterotrimerization system.; Nat.Methods, 17:928-936, 2020; PubMed: 32747768; DOI: 10.1038/s41592-020-0913-x

実験手法

X-RAY DIFFRACTION (2.92 Å)