6M3D

X-ray crystal structure of tandemly connected engrailed homeodomains (EHD) with R53A mutations and DNA complex

Summary for 6M3D

• Entry DOI: 10.2210/pdb6m3d/pdb
• Descriptor: DNA (5'-D(*TP*AP*AP*TP*CP*CP*TP*AP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*TP*AP*GP*GP*AP*TP*TP*A)-3'), Segmentation polarity homeobox protein engrailed,Segmentation polarity homeobox protein engrailed, ... (5 entities in total)
• Functional Keywords: homeodomain fold, protein-dna complex, genome editing, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Drosophila melanogaster (Fruit fly); More
• Total number of polymer chains: 3
• Total formula weight: 24690.41

Authors

Sunami, T.,Hirano, Y.,Tamada, T.,Kono, H. (deposition date: 2020-03-03, release date: 2020-09-16, Last modification date: 2023-11-29)

• Primary citation: Sunami, T.,Hirano, Y.,Tamada, T.,Kono, H.; Structural basis for designing an array of engrailed homeodomains.; Acta Crystallogr D Struct Biol, 76:824-833, 2020; PubMed: 32876058; DOI: 10.1107/S2059798320009237

Experimental method

X-RAY DIFFRACTION (1.6 Å)