6M3D

X-ray crystal structure of tandemly connected engrailed homeodomains (EHD) with R53A mutations and DNA complex

6M3D の概要

• エントリーDOI: 10.2210/pdb6m3d/pdb
• 分子名称: DNA (5'-D(*TP*AP*AP*TP*CP*CP*TP*AP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*TP*AP*GP*GP*AP*TP*TP*A)-3'), Segmentation polarity homeobox protein engrailed,Segmentation polarity homeobox protein engrailed, ... (5 entities in total)
• 機能のキーワード: homeodomain fold, protein-dna complex, genome editing, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Drosophila melanogaster (Fruit fly); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 24690.41

構造登録者

Sunami, T.,Hirano, Y.,Tamada, T.,Kono, H. (登録日: 2020-03-03, 公開日: 2020-09-16, 最終更新日: 2023-11-29)

• 主引用文献: Sunami, T.,Hirano, Y.,Tamada, T.,Kono, H.; Structural basis for designing an array of engrailed homeodomains.; Acta Crystallogr D Struct Biol, 76:824-833, 2020; PubMed: 32876058; DOI: 10.1107/S2059798320009237

実験手法

X-RAY DIFFRACTION (1.6 Å)