6M1J

The DNA Gyrase B ATP binding domain of PSEUDOMONAS AERUGINOSA in complex with compound 12x

6M1J の概要

• エントリーDOI: 10.2210/pdb6m1j/pdb
• 分子名称: DNA gyrase subunit B, DIMETHYL SULFOXIDE, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: dna gyrase, topoisomerase, atpase domain, isomerase
• 由来する生物種: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49273.82

構造登録者

Xu, Z.H.,Zhou, Z. (登録日: 2020-02-26, 公開日: 2020-09-02, 最終更新日: 2023-11-29)

• 主引用文献: Hu, Y.,Shi, H.,Zhou, M.,Ren, Q.,Zhu, W.,Zhang, W.,Zhang, Z.,Zhou, C.,Liu, Y.,Ding, X.,Shen, H.C.,Yan, S.F.,Dey, F.,Wu, W.,Zhai, G.,Zhou, Z.,Xu, Z.,Ji, Y.,Lv, H.,Jiang, T.,Wang, W.,Xu, Y.,Vercruysse, M.,Yao, X.,Mao, Y.,Yu, X.,Bradley, K.,Tan, X.; Discovery of Pyrido[2,3-b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV.; J.Med.Chem., 63:9623-9649, 2020; PubMed: 32787097; DOI: 10.1021/acs.jmedchem.0c00768

実験手法

X-RAY DIFFRACTION (1.701 Å)