6LZB
crystal structure of Human Methionine aminopeptidase (HsMetAP1b) in complex with AN-P2-5H-06
Summary for 6LZB
| Entry DOI | 10.2210/pdb6lzb/pdb |
| Descriptor | Methionine aminopeptidase 1, COBALT (II) ION, 1-[(3-methoxyphenyl)methyl]-~{N}-oxidanyl-pyrrolo[2,3-b]pyridine-5-carboxamide, ... (7 entities in total) |
| Functional Keywords | methionine aminopeptidase, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 37674.68 |
| Authors | sandeep, C.B.,Addlagatta, A. (deposition date: 2020-02-18, release date: 2021-02-24, Last modification date: 2023-11-29) |
| Primary citation | Bala, S.,Yellamanda, K.V.,Kadari, A.,Ravinuthala, V.S.U.,Kattula, B.,Singh, O.V.,Gundla, R.,Addlagatta, A. Selective inhibition of Helicobacter pylori methionine aminopeptidase by azaindole hydroxamic acid derivatives: Design, synthesis, in vitro biochemical and structural studies. Bioorg.Chem., 115:105185-105185, 2021 Cited by PubMed: 34329997DOI: 10.1016/j.bioorg.2021.105185 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.29 Å) |
Structure validation
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