6LUE

Crystal structure of mouse Cryptochrome 1 in complex with compound KL201

Summary for 6LUE

Entry DOI	10.2210/pdb6lue/pdb
Descriptor	Cryptochrome-1, 2-bromanyl-N-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)benzamide (3 entities in total)
Functional Keywords	cryptochrome, cry, circadian clock, kl201, circadian clock protein
Biological source	Mus musculus (Mouse)
Total number of polymer chains	2
Total formula weight	115520.03
Authors	Miller, S.,Aikawa, Y.,Hirota, T. (deposition date: 2020-01-27, release date: 2020-06-10, Last modification date: 2023-11-29)
Primary citation	Miller, S.,Aikawa, Y.,Sugiyama, A.,Nagai, Y.,Hara, A.,Oshima, T.,Amaike, K.,Kay, S.A.,Itami, K.,Hirota, T. An Isoform-Selective Modulator of Cryptochrome 1 Regulates Circadian Rhythms in Mammals. Cell Chem Biol, 27:1192-1198.e5, 2020 Cited by PubMed: 32502390 DOI: 10.1016/j.chembiol.2020.05.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation