6LSE

Crystal structure of the enterovirus 71 polymerase elongation complex (C3S6A/C3S6B form)

Summary for 6LSE

• Entry DOI: 10.2210/pdb6lse/pdb
• Descriptor: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*CP*U)-3'), ... (7 entities in total)
• Functional Keywords: polymerase-rna complex, elongation, translocation, transferase, transferase-rna complex, transferase/rna
• Biological source: Human enterovirus 71 (EV71); More
• Total number of polymer chains: 3
• Total formula weight: 71220.38

Authors

Wang, M.,Shu, B.,Jing, X.,Gong, P. (deposition date: 2020-01-17, release date: 2020-04-29, Last modification date: 2023-11-29)

• Primary citation: Wang, M.,Li, R.,Shu, B.,Jing, X.,Ye, H.Q.,Gong, P.; Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.; Nat Commun, 11:2605-2605, 2020; PubMed: 32451382; DOI: 10.1038/s41467-020-16234-4

Experimental method

X-RAY DIFFRACTION (2.25 Å)