6LPB
Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein
Summary for 6LPB
Entry DOI | 10.2210/pdb6lpb/pdb |
EMDB information | 0940 |
Descriptor | Pituitary adenylate cyclase-activating polypeptide, Pituitary adenylate cyclase-activating polypeptide type I receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | class b gpcr, pacap, pac1r, signaling protein-hormone complex, signaling protein/hormone |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 141495.37 |
Authors | Kobayashi, K.,Shihoya, W.,Nishizawa, T.,Nureki, O. (deposition date: 2020-01-09, release date: 2020-03-11, Last modification date: 2024-10-09) |
Primary citation | Kobayashi, K.,Shihoya, W.,Nishizawa, T.,Kadji, F.M.N.,Aoki, J.,Inoue, A.,Nureki, O. Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein. Nat.Struct.Mol.Biol., 27:274-280, 2020 Cited by PubMed: 32157248DOI: 10.1038/s41594-020-0386-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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