6LPB

Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein

6LPB の概要

• エントリーDOI: 10.2210/pdb6lpb/pdb
• EMDBエントリー: 0940
• 分子名称: Pituitary adenylate cyclase-activating polypeptide, Pituitary adenylate cyclase-activating polypeptide type I receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
• 機能のキーワード: class b gpcr, pacap, pac1r, signaling protein-hormone complex, signaling protein/hormone
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 141495.37

構造登録者

Kobayashi, K.,Shihoya, W.,Nishizawa, T.,Nureki, O. (登録日: 2020-01-09, 公開日: 2020-03-11, 最終更新日: 2020-03-25)

• 主引用文献: Kobayashi, K.,Shihoya, W.,Nishizawa, T.,Kadji, F.M.N.,Aoki, J.,Inoue, A.,Nureki, O.; Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein.; Nat.Struct.Mol.Biol., 27:274-280, 2020; PubMed: 32157248; DOI: 10.1038/s41594-020-0386-8

実験手法

ELECTRON MICROSCOPY (3.9 Å)