6LO2

Crystal structure of EED in complex with EZH2 peptide and compound 11#

Summary for 6LO2

• Entry DOI: 10.2210/pdb6lo2/pdb
• Descriptor: Polycomb protein EED, Histone-lysine N-methyltransferase EZH2, 8-[4-[(dimethylamino)methyl]phenyl]-N-[(2-methoxyphenyl)methyl]-[1,2,4]triazolo[4,3-a]pyridin-5-amine, ... (4 entities in total)
• Functional Keywords: hts hit optimization, peptide binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 92731.78

Authors

Zhao, K.,Zhao, M.,Luo, X.,Zhang, H.,Chen, Z. (deposition date: 2020-01-02, release date: 2021-07-07, Last modification date: 2023-11-29)

• Primary citation: Zhao, K.,Zhao, M.,Luo, X.,Zhang, H.; Structure of EED in complex with EZH2 peptide and cmpd20; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.21 Å)