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6LMK

Cryo-EM structure of the human glucagon receptor in complex with Gs

Summary for 6LMK
Entry DOI10.2210/pdb6lmk/pdb
EMDB information0917
DescriptorGuanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
Functional Keywordsglucagon receptor, gpcr, gs protein, signaling protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains6
Total formula weight159314.58
Authors
Qiao, A.,Han, S.,Tai, L.,Sun, F.,Zhao, Q.,Wu, B. (deposition date: 2019-12-26, release date: 2020-04-01)
Primary citationQiao, A.,Han, S.,Li, X.,Li, Z.,Zhao, P.,Dai, A.,Chang, R.,Tai, L.,Tan, Q.,Chu, X.,Ma, L.,Thorsen, T.S.,Reedtz-Runge, S.,Yang, D.,Wang, M.W.,Sexton, P.M.,Wootten, D.,Sun, F.,Zhao, Q.,Wu, B.
Structural basis of Gsand Girecognition by the human glucagon receptor.
Science, 367:1346-1352, 2020
Cited by
PubMed: 32193322
DOI: 10.1126/science.aaz5346
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.7 Å)
Structure validation

217705

數據於2024-03-27公開中

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