6LLC
Discovery of A Dual Inhibitor of NQO1 and GSTP1 for Treating Malignant Glioblastoma
Summary for 6LLC
Entry DOI | 10.2210/pdb6llc/pdb |
Descriptor | NAD(P)H dehydrogenase [quinone] 1, FLAVIN-ADENINE DINUCLEOTIDE, 5-methyl-N-(5-nitro-1,3-thiazol-2-yl)-3-phenyl-1,2-oxazole-4-carboxamide, ... (5 entities in total) |
Functional Keywords | oxidative stress, gbm, small molecular inhibitor, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 12 |
Total formula weight | 381770.35 |
Authors | |
Primary citation | Lei, K.,Gu, X.,Alvarado, A.G.,Du, Y.,Luo, S.,Ahn, E.H.,Kang, S.S.,Ji, B.,Liu, X.,Mao, H.,Fu, H.,Kornblum, H.I.,Jin, L.,Li, H.,Ye, K. Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma. J Hematol Oncol, 13:141-141, 2020 Cited by PubMed: 33087132DOI: 10.1186/s13045-020-00979-y PDB entries with the same primary citation |
Experimental method |
Structure validation
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