6LJA

Crystal Structure of exoHep from Bacteroides intestinalis DSM 17393 complexed with disaccharide product

Summary for 6LJA

Entry DOI	10.2210/pdb6lja/pdb
Related PRD ID	PRD_900026
Descriptor	Heparinase II/III-like protein, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, ... (4 entities in total)
Functional Keywords	heparin, heparan sulfate, heparinase, lyase
Biological source	Bacteroides intestinalis DSM 17393
Total number of polymer chains	1
Total formula weight	100715.09
Authors	Zhang, Q.D.,Cao, H.Y.,Wei, L.,Li, F.C.,Zhang, Y.Z. (deposition date: 2019-12-13, release date: 2020-12-23, Last modification date: 2024-03-27)
Primary citation	Zhang, Q.,Cao, H.Y.,Wei, L.,Lu, D.,Du, M.,Yuan, M.,Shi, D.,Chen, X.,Wang, P.,Chen, X.L.,Chi, L.,Zhang, Y.Z.,Li, F. Discovery of exolytic heparinases and their catalytic mechanism and potential application. Nat Commun, 12:1263-1263, 2021 Cited by PubMed: 33627653 DOI: 10.1038/s41467-021-21441-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.978 Å)

Structure validation