6LDT

K245A mutant of L-tyrosine decarboxylase from Methanocaldococcus jannaschii complexed with a post-decarboxylation quinonoid-like intermediate formed with L-tyrosine

6LDT の概要

• エントリーDOI: 10.2210/pdb6ldt/pdb
• 関連するPDBエントリー: 6JY1 6LDR 6LDS
• 分子名称: L-tyrosine/L-aspartate decarboxylase, GLYCEROL, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: plp dependent decarboxylase, catalytic domain, models, molecular, protein conformation, plp, tyrosine, quinonoid, tyrosine decarboxylase, structure-activity relationship, dunathan alignment, lyase
• 由来する生物種: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48339.38

構造登録者

Manoj, N.,Chellam Gayathri, S. (登録日: 2019-11-23, 公開日: 2020-12-02, 最終更新日: 2023-11-22)

• 主引用文献: Chellam Gayathri, S.,Manoj, N.; Structural insights into the mechanism of internal aldimine formation and catalytic loop dynamics in an archaeal Group II decarboxylase.; J.Struct.Biol., 208:137-151, 2019; PubMed: 31445086; DOI: 10.1016/j.jsb.2019.08.009

実験手法

X-RAY DIFFRACTION (1.93 Å)