6LCB

Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009

6LCB の概要

• エントリーDOI: 10.2210/pdb6lcb/pdb
• 分子名称: Segment polarity protein dishevelled homolog DVL-1, 2-[[3-[(2E)-2-[1,3-bis(oxidanylidene)-1-phenyl-butan-2-ylidene]hydrazinyl]phenyl]sulfonylamino]benzoic acid, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: wnt signaling pathway, signaling protein, developmental protein, protein binding, dvl, inhibitor of protein-protein interactions
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11332.60

構造登録者

Yasukochi, S.,Numoto, N.,Tenno, N.,Tenno, T.,Ito, N.,Hiroaki, H. (登録日: 2019-11-18, 公開日: 2020-11-25, 最終更新日: 2023-11-22)

• 主引用文献: Yasukochi, S.,Numoto, N.,Tenno, N.,Tenno, T.,Ito, N.,Hiroaki, H.; Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009; To Be Published,

実験手法

X-RAY DIFFRACTION (1.4 Å)