6L5Z

Crystal strucutre of AF9 YEATS domain in complex with a cyclopeptide inhibitor

Summary for 6L5Z

• Entry DOI: 10.2210/pdb6l5z/pdb
• Descriptor: Protein AF-9, SC0-ALO-ALA-SC3-SC4-NH2 (3 entities in total)
• Functional Keywords: yeats domain, complex, cyclopeptide inhibitor, , transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 17426.07

Authors

Li, Y.,Chen, G.,Li, H. (deposition date: 2019-10-25, release date: 2020-10-28, Last modification date: 2023-11-22)

• Primary citation: Jiang, Y.,Chen, G.,Li, X.M.,Liu, S.,Tian, G.,Li, Y.,Li, X.,Li, H.,Li, X.D.; Selective Targeting of AF9 YEATS Domain by Cyclopeptide Inhibitors with Preorganized Conformation.; J.Am.Chem.Soc., 142:21450-21459, 2020; PubMed: 33306911; DOI: 10.1021/jacs.0c10324

Experimental method

X-RAY DIFFRACTION (3.05 Å)