6L2P
Threonyl-tRNA synthetase from Salmonella enterica in the apo form
Summary for 6L2P
Entry DOI | 10.2210/pdb6l2p/pdb |
Descriptor | Threonine--tRNA ligase, ZINC ION (3 entities in total) |
Functional Keywords | trna synthetase, drug target, homodimer, ligase |
Biological source | Salmonella enterica subsp. enterica serovar Cubana str. 76814 |
Total number of polymer chains | 2 |
Total formula weight | 96059.84 |
Authors | |
Primary citation | Guo, J.,Chen, B.,Yu, Y.,Cheng, B.,Cheng, Y.,Ju, Y.,Gu, Q.,Xu, J.,Zhou, H. Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hopping. Eur.J.Med.Chem., 187:111941-111941, 2019 Cited by PubMed: 31821989DOI: 10.1016/j.ejmech.2019.111941 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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