6L21

Crystal structure of CK2a1 H160A with hematein

Summary for 6L21

Entry DOI	10.2210/pdb6l21/pdb
Descriptor	Casein kinase II subunit alpha, (6aR)-3,4,6a,10-tetrakis(oxidanyl)-6,7-dihydroindeno[2,1-c]chromen-9-one (3 entities in total)
Functional Keywords	protein kinase, transferase, inhibitor, complex
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	40711.39
Authors	Tsuyuguchi, M.,Kinoshita, T. (deposition date: 2019-10-02, release date: 2020-02-26, Last modification date: 2023-11-22)
Primary citation	Tsuyuguchi, M.,Nakaniwa, T.,Hirasawa, A.,Nakanishi, I.,Kinoshita, T. Structural insights for producing CK2 alpha 1-specific inhibitors. Bioorg.Med.Chem.Lett., 30:126837-126837, 2020 Cited by PubMed: 31859160 DOI: 10.1016/j.bmcl.2019.126837 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05451776886 Å)

Structure validation