6KVS

Staphylococcus aureus FabH with covalent inhibitor Oxa1

Summary for 6KVS

• Entry DOI: 10.2210/pdb6kvs/pdb
• Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 3, 4-chloranyl-N-[[cyclopropylmethyl(methanoyl)amino]methyl]benzamide (3 entities in total)
• Functional Keywords: covalent inhibitor, complex, ketoacyl-acp synthase iii, antibiotic, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Staphylococcus aureus (strain Mu3 / ATCC 700698)
• Total number of polymer chains: 2
• Total formula weight: 68366.24

Authors

Yuan, Y.,Wang, J. (deposition date: 2019-09-05, release date: 2020-09-09, Last modification date: 2023-11-22)

• Primary citation: Qiu, X.,Choudhry, A.E.; Crystal Structure of S. aureus FabH, beta-ketoacyl carrier protein synthase; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)