6KR5

Crystal structure of O-Acetyl Serine Sulfhydrylase isoform 3 from Entamoeba histolytica

Summary for 6KR5

Entry DOI	10.2210/pdb6kr5/pdb
Descriptor	Cysteine synthase 3, PYRIDOXAL-5'-PHOSPHATE (3 entities in total)
Functional Keywords	o-acetylserine sulphydralase, cysteine synthase transferase o-acetyl-l-serine(thiol)lyase, transferase
Biological source	Entamoeba histolytica
Total number of polymer chains	2
Total formula weight	73476.60
Authors	Dharavath, S.,Gourinath, S. (deposition date: 2019-08-21, release date: 2020-09-09, Last modification date: 2023-11-22)
Primary citation	Dharavath, S.,Vijayan, R.,Kumari, K.,Tomar, P.,Gourinath, S. Crystal structure of O-Acetylserine sulfhydralase (OASS) isoform 3 from Entamoeba histolytica: Pharmacophore-based virtual screening and validation of novel inhibitors. Eur.J.Med.Chem., 192:112157-112157, 2020 Cited by PubMed: 32145643 DOI: 10.1016/j.ejmech.2020.112157 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.544 Å)

Structure validation