6KPC
Crystal structure of an agonist bound GPCR
Summary for 6KPC
Entry DOI | 10.2210/pdb6kpc/pdb |
Descriptor | Cannabinoid receptor 2,Endolysin, 7-[(6aR,9R,10aR)-1-Hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-3-yl]- 7-methyloctanenitrile (2 entities in total) |
Functional Keywords | gpcr, lcp, agonist, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 56609.50 |
Authors | |
Primary citation | Hua, T.,Li, X.,Wu, L.,Iliopoulos-Tsoutsouvas, C.,Wang, Y.,Wu, M.,Shen, L.,Johnston, C.A.,Nikas, S.P.,Song, F.,Song, X.,Yuan, S.,Sun, Q.,Wu, Y.,Jiang, S.,Grim, T.W.,Benchama, O.,Stahl, E.L.,Zvonok, N.,Zhao, S.,Bohn, L.M.,Makriyannis, A.,Liu, Z.J. Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-GiComplex Structures. Cell, 180:655-, 2020 Cited by PubMed: 32004463DOI: 10.1016/j.cell.2020.01.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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