6KMZ
caspase-4 P22/P10 C258A in complex with human GSDMD-C domain
Summary for 6KMZ
Entry DOI | 10.2210/pdb6kmz/pdb |
Descriptor | Caspase-4, Gasdermin-D, ... (4 entities in total) |
Functional Keywords | pyroptosis, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 167277.57 |
Authors | |
Primary citation | Wang, K.,Sun, Q.,Zhong, X.,Zeng, M.,Zeng, H.,Shi, X.,Li, Z.,Wang, Y.,Zhao, Q.,Shao, F.,Ding, J. Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis. Cell, 180:941-, 2020 Cited by PubMed: 32109412DOI: 10.1016/j.cell.2020.02.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.61 Å) |
Structure validation
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