6KLK
Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-FU
Summary for 6KLK
Entry DOI | 10.2210/pdb6klk/pdb |
Descriptor | D-hydantoinase/dihydropyrimidinase, 5-FLUOROURACIL, ZINC ION, ... (4 entities in total) |
Functional Keywords | hydrolase, dihydropyrimidinase |
Biological source | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
Total number of polymer chains | 2 |
Total formula weight | 105023.40 |
Authors | Huang, Y.H.,Chen, I.C.,Huang, C.Y. (deposition date: 2019-07-30, release date: 2019-11-06, Last modification date: 2023-11-22) |
Primary citation | Huang, Y.H.,Ning, Z.J.,Huang, C.Y. Crystal structure of dihydropyrimidinase in complex with anticancer drug 5-fluorouracil. Biochem.Biophys.Res.Commun., 519:160-165, 2019 Cited by PubMed: 31481233DOI: 10.1016/j.bbrc.2019.08.153 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.759 Å) |
Structure validation
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