6KJF
lovastatin esterase PcEST in complex with simvastatin
Summary for 6KJF
Entry DOI | 10.2210/pdb6kjf/pdb |
Descriptor | Pc15g00720 protein, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, Simvastatin acid, ... (4 entities in total) |
Functional Keywords | family viii esterase, lovastatin hydrolysis, monacolin j, simvastatin, hydrolase |
Biological source | Penicillium rubens Wisconsin 54-1255 |
Total number of polymer chains | 2 |
Total formula weight | 88428.15 |
Authors | Liang, Y.J.,Lu, X.F. (deposition date: 2019-07-22, release date: 2019-12-25, Last modification date: 2023-11-22) |
Primary citation | Liang, Y.J.,Lu, X.F. Structural insights into the catalytic mechanism of lovastatin hydrolase J.Biol.Chem., 2019 Cited by DOI: 10.1074/jbc.RA119.011936PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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