6KJE
lovastatin esterase PcEST in complex with monacolin J
Summary for 6KJE
| Entry DOI | 10.2210/pdb6kje/pdb |
| Descriptor | Pc15g00720 protein, (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, ... (5 entities in total) |
| Functional Keywords | family viii esterase, lovastatin hydrolysis, monacolin j, simvastatin, hydrolase |
| Biological source | Penicillium rubens Wisconsin 54-1255 |
| Total number of polymer chains | 2 |
| Total formula weight | 87983.53 |
| Authors | Liang, Y.J.,Lu, X.F. (deposition date: 2019-07-22, release date: 2019-12-25, Last modification date: 2023-11-22) |
| Primary citation | Liang, Y.J.,Lu, X.F. Structural insights into the catalytic mechanism of lovastatin hydrolase J.Biol.Chem., 2019 Cited by DOI: 10.1074/jbc.RA119.011936PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.484 Å) |
Structure validation
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