6KJE

lovastatin esterase PcEST in complex with monacolin J

Summary for 6KJE

Entry DOI	10.2210/pdb6kje/pdb
Descriptor	Pc15g00720 protein, (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, ... (5 entities in total)
Functional Keywords	family viii esterase, lovastatin hydrolysis, monacolin j, simvastatin, hydrolase
Biological source	Penicillium rubens Wisconsin 54-1255
Total number of polymer chains	2
Total formula weight	87983.53
Authors	Liang, Y.J.,Lu, X.F. (deposition date: 2019-07-22, release date: 2019-12-25, Last modification date: 2023-11-22)
Primary citation	Liang, Y.J.,Lu, X.F. Structural insights into the catalytic mechanism of lovastatin hydrolase J.Biol.Chem., 2019 Cited by DOI: 10.1074/jbc.RA119.011936 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.484 Å)

Structure validation