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6KHE

Crystal structure of CLK2 in complex with CX-4945

Summary for 6KHE
Entry DOI10.2210/pdb6khe/pdb
DescriptorDual specificity protein kinase CLK2, 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid (3 entities in total)
Functional Keywordscdc2-like kinase, casein kinase, cx-4945, alternative splicing, splicing, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight60562.16
Authors
Lee, J.Y.,Yun, J.S.,Jin, H.,Chang, J.H. (deposition date: 2019-07-15, release date: 2019-10-02, Last modification date: 2024-03-27)
Primary citationLee, J.Y.,Yun, J.S.,Kim, W.K.,Chun, H.S.,Jin, H.,Cho, S.,Chang, J.H.
Structural Basis for the Selective Inhibition of Cdc2-Like Kinases by CX-4945.
Biomed Res Int, 2019:6125068-6125068, 2019
Cited by
PubMed: 31531359
DOI: 10.1155/2019/6125068
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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