6KEB
Structure basis for Diltiazem block of a voltage-gated calcium channel
Summary for 6KEB
Entry DOI | 10.2210/pdb6keb/pdb |
Descriptor | Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | tetrameric, voltage-gated ion channel, voltage-gated calcium channel block, membrane protein, transport protein |
Biological source | Arcobacter butzleri |
Total number of polymer chains | 4 |
Total formula weight | 140565.16 |
Authors | Tang, L. (deposition date: 2019-07-04, release date: 2019-10-23, Last modification date: 2024-05-29) |
Primary citation | Tang, L.,Gamal El-Din, T.M.,Lenaeus, M.J.,Zheng, N.,Catterall, W.A. Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+Channel. Mol.Pharmacol., 96:485-492, 2019 Cited by PubMed: 31391290DOI: 10.1124/mol.119.117531 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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