6KDY

Crystal structure of the alpha bata heterodimer of human IDH3 in complex with NAD.

Summary for 6KDY

• Entry DOI: 10.2210/pdb6kdy/pdb
• Descriptor: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (7 entities in total)
• Functional Keywords: nad dependent isocitrate dehydrogenase, oxidoreductase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 310201.30

Authors

Sun, P.,Ding, J. (deposition date: 2019-07-03, release date: 2019-09-25, Last modification date: 2023-11-22)

• Primary citation: Sun, P.,Ma, T.,Zhang, T.,Zhu, H.,Zhang, J.,Liu, Y.,Ding, J.; Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase.; J.Biol.Chem., 294:16214-16227, 2019; PubMed: 31515270; DOI: 10.1074/jbc.RA119.010099

Experimental method

X-RAY DIFFRACTION (3.02 Å)