6KDE

Crystal structure of the alpha beta heterodimer of human IDH3 in complex with Ca(2+)

Summary for 6KDE

Entry DOI	10.2210/pdb6kde/pdb
Descriptor	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, CALCIUM ION (3 entities in total)
Functional Keywords	nad dependent isocitrate dehydrogenase, oxidoreductase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	153140.09
Authors	Sun, P.,Ding, J. (deposition date: 2019-07-02, release date: 2019-09-25, Last modification date: 2023-11-22)
Primary citation	Sun, P.,Ma, T.,Zhang, T.,Zhu, H.,Zhang, J.,Liu, Y.,Ding, J. Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase. J.Biol.Chem., 294:16214-16227, 2019 Cited by PubMed: 31515270 DOI: 10.1074/jbc.RA119.010099 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.999 Å)

Structure validation