6KDA

Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpG site

6KDA の概要

• エントリーDOI: 10.2210/pdb6kda/pdb
• 分子名称: DNA (cytosine-5)-methyltransferase 3B, DNA (cytosine-5)-methyltransferase 3-like, DNA (25-MER), ... (5 entities in total)
• 機能のキーワード: dnmt3b, dna methyltransferase, complex, transferase, transferase-dna complex, transferase/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 128846.77

構造登録者

Lin, C.-C.,Chen, Y.-P.,Yang, W.-Z.,Shen, C.-K.,Yuan, H.S. (登録日: 2019-07-01, 公開日: 2020-02-19, 最終更新日: 2023-11-22)

• 主引用文献: Lin, C.C.,Chen, Y.P.,Yang, W.Z.,Shen, J.C.K.,Yuan, H.S.; Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.; Nucleic Acids Res., 48:3949-3961, 2020; PubMed: 32083663; DOI: 10.1093/nar/gkaa111

実験手法

X-RAY DIFFRACTION (2.909 Å)