6KA5

Crystal structure of a class C beta-lactamase in complex with cefoxitin

Summary for 6KA5

Entry DOI	10.2210/pdb6ka5/pdb
Descriptor	Beta-lactamase, (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid (3 entities in total)
Functional Keywords	class c-lactamase, acyl-enzyme complex, hydrolase
Biological source	Klebsiella pneumoniae
Total number of polymer chains	1
Total formula weight	41081.74
Authors	Bae, D.W.,Jung, Y.E.,An, Y.J.,Na, J.H.,Cha, S.S. (deposition date: 2019-06-20, release date: 2019-10-16, Last modification date: 2023-11-29)
Primary citation	Bae, D.W.,Jung, Y.E.,An, Y.J.,Na, J.H.,Cha, S.S. Structural Insights into Catalytic Relevances of Substrate Poses in ACC-1. Antimicrob.Agents Chemother., 63:-, 2019 Cited by PubMed: 31451494 DOI: 10.1128/AAC.01411-19 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation