6JUJ

Crystal structure of Formate dehydrogenase mutant V198I/C256I/P260S/E261P/S381N/S383F from Pseudomonas sp. 101in complex with non-natural cofactor Nicotinamide Cytosine Dinucleotide

6JUJ の概要

• エントリーDOI: 10.2210/pdb6juj/pdb
• 分子名称: Formate dehydrogenase, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: formate dehydrogenase, oxidoreductase
• 由来する生物種: Pseudomonas sp. 101 (Achromobacter parvulus T1)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 90267.72

構造登録者

Feng, Y.,Guo, X.,Xue, S.,Zhao, Z. (登録日: 2019-04-14, 公開日: 2020-05-13, 最終更新日: 2023-11-22)

• 主引用文献: Guo, X.,Wang, X.,Liu, Y.,Li, Q.,Wang, J.,Liu, W.,Zhao, Z.K.; Structure-Guided Design of Formate Dehydrogenase for Regeneration of a Non-Natural Redox Cofactor.; Chemistry, 26:16611-16615, 2020; PubMed: 32815230; DOI: 10.1002/chem.202003102

実験手法

X-RAY DIFFRACTION (2.183 Å)