6JOI

Crystal structure of PDGFRA T674I in complex with crenolanib by co-crystallization

6JOI の概要

• エントリーDOI: 10.2210/pdb6joi/pdb
• 分子名称: Platelet-derived growth factor receptor alpha, 1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine (3 entities in total)
• 機能のキーワード: pdgfra, t674i, inhibitor, crenolanib, oncoprotein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43473.88

構造登録者

Liang, L.,Yan, X.E.,Yun, C.H. (登録日: 2019-03-22, 公開日: 2020-03-25, 最終更新日: 2023-11-22)

• 主引用文献: Liang, L.,Yan, X.E.; Crystal structure of PDGFRA T674I in complex with crenolanib by co-crystallization; To Be Published,

実験手法

X-RAY DIFFRACTION (3.1 Å)