6JLV

Near-Atomic Resolution Structure of the CYP102A1 Haem Domain with N-Abietoyl-L-Tryptophan

Summary for 6JLV

• Entry DOI: 10.2210/pdb6jlv/pdb
• Descriptor: Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, (2S)-2-[[(1R,4aR,4bR,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,4b,5,6,10,10a-octahydrophenanthren-1-yl]carbonylamino]-3-( 1H-indol-3-yl)propanoic acid, ... (7 entities in total)
• Functional Keywords: monooxygenase, oxidoreductase
• Biological source: Bacillus megaterium
• Total number of polymer chains: 2
• Total formula weight: 108922.09

Authors

Stanfield, J.K.,Kasai, C.,Sugimoto, H.,Shiro, Y.,Watanabe, Y.,Shoji, O. (deposition date: 2019-03-07, release date: 2020-03-18, Last modification date: 2023-11-22)

• Primary citation: Stanfield, J.K.,Omura, K.,Matsumoto, A.,Kasai, C.,Sugimoto, H.,Shiro, Y.,Watanabe, Y.,Shoji, O.; Crystals in Minutes: Instant On-Site Microcrystallisation of Various Flavours of the CYP102A1 (P450BM3) Haem Domain.; Angew.Chem.Int.Ed.Engl., 59:7611-7618, 2020; PubMed: 32157795; DOI: 10.1002/anie.201913407

Experimental method

X-RAY DIFFRACTION (1.22 Å)