6JFV
The crystal structure of 2B-2B complex from keratins 5 and 14 (C367A mutant of K14)
Summary for 6JFV
Entry DOI | 10.2210/pdb6jfv/pdb |
Descriptor | Keratin, type I cytoskeletal 14, Keratin, type II cytoskeletal 5 (3 entities in total) |
Functional Keywords | intermediate filaments, keratinocytes, skin, epithelium, protein self-assembly, cytosolic protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 45061.58 |
Authors | Kim, M.S.,Lee, C.H.,Coulombe, P.A.,Leahy, D.J. (deposition date: 2019-02-12, release date: 2020-01-22, Last modification date: 2024-05-29) |
Primary citation | Lee, C.H.,Kim, M.S.,Li, S.,Leahy, D.J.,Coulombe, P.A. Structure-Function Analyses of a Keratin Heterotypic Complex Identify Specific Keratin Regions Involved in Intermediate Filament Assembly. Structure, 28:355-362.e4, 2020 Cited by PubMed: 31995743DOI: 10.1016/j.str.2020.01.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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