6JDE

crystal structure of a DNA repair protein

6JDE の概要

• エントリーDOI: 10.2210/pdb6jde/pdb
• 分子名称: Putative DNA repair helicase RadD, ZINC ION (3 entities in total)
• 機能のキーワード: dna repair protein, hydrolase
• 由来する生物種: Escherichia coli K-12
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 133148.90

構造登録者

Yan, X.X.,Tang, Q. (登録日: 2019-02-01, 公開日: 2019-06-26, 最終更新日: 2024-03-27)

主引用文献

Kuang, X.,Tang, Q.,Liu, Y.P.,Yan, X.X.,Xu, W.
Crystal structure of a novel ATPase RadD from Escherichia coli.
Proteins, 87:791-795, 2019

PubMed Abstract: The helicase superfamily 2 (SF2) proteins are involved in essentially every step in DNA and RNA metabolism. The radD (yejH) gene, which belongs to SF2, plays an important role in DNA repair. The RadD protein includes all seven conserved SF2 motifs and has shown ATPase activity. Here, we first reported the structure of RadD from Escherichia coli containing two RecA-like domains, a zinc finger motif, and a C-terminal domain. Based on the structure of RadD and other SF2 proteins, we then built a model of the RedD-ATP complex.

PubMed: 31035307
DOI: 10.1002/prot.25704

実験手法

X-RAY DIFFRACTION (2.8 Å)